| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92b2b9c0657d1fd1f68c5ddd9d16da49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a34ba4909d70bdc89c6b87879121053
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a360c61f0dbd69db62654df57d0a58ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b23f5607aa63fdcfaef3ca9ee364108c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_677137274f8c3c0f60659d437587d931 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 |
| filingDate |
2011-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67e506a009d92a0ae6ecf99dcf92f675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba48a7edb7f5627db6aa2cb5d4f03e5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfff152e34a1ce99dcc02e8228d37a34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9abda428b2530da3650e29b91ba7711d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_335388a9df01a804ffdcacb8eade2783 |
| publicationDate |
2012-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8148106-B2 |
| titleOfInvention |
Antagonist anti-Notch3 antibodies and their use in the prevention and treatment of Notch3-related diseases |
| abstract |
The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016007775-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9914774-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9873734-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8956811-B2 |
| priorityDate |
2006-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |