| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ebd6e0b080c9eb97a608397038eae48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05d7bcc255bbbea776e54cf3c2ccd6f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a274fd325ebe6817ff8922edc54ddd9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dcfcca6a451509c39b76a510a63ba258 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-061
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6879
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0612
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
2009-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3df5edc5c36b4d59a2051a44460a4b03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46c0ca55ed740337c1ed5feb2d3570b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b11009066782116b327ef4d384335a3 |
| publicationDate |
2012-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8138319-B2 |
| titleOfInvention |
Sperm cell separation methods and compositions containing aptamers or nucleic acid sequences for use therein |
| abstract |
The present invention provides an aptamer or pool of aptamers (nucleic acid sequences) that bind(s) to a target molecule on the surface, accessible from the surface or inside of a mammalian sperm cell and a method for producing the aptamers. The method comprises contacting a collection of different nucleic acid molecules with the target molecule under conditions favorable for binding between at least one of the nucleic acid molecules and the target molecule, to form at least one complex comprising the nucleic acid molecule bound to the target molecule, wherein each of the nucleic acid molecules comprises at least one segment of randomized nucleotide sequences. The complexes are then separated from the unbound nucleic acid molecules and unbound target molecules, and the bound nucleic acid molecule is recovered from the separated complex. The aptamers are used to separate sperm cells based upon sperm cell qualities, such as whether the cells contain X chromosomes or Y chromosomes. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10456170-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9546397-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017233739-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11008575-B2 |
| priorityDate |
2005-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |