Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f79749e86afce9444a364ab60ca3584 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7bf3a5c3139e025ed44112e9948da59f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd4c3514305be29522677d7f2da7eef8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07f8378d083de25066eab97fe4aa1c5c |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01J4-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-21 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01J4-00 |
filingDate |
2005-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa80b9ad399e9ae54210232a05709297 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae83cc7763a2b2cb84e19d6f230d7648 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d6de815c0855170d311263bde885b26 |
publicationDate |
2012-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8134707-B2 |
titleOfInvention |
On-chip polarimetry for high-throughput screening of nanoliter and smaller sample volumes |
abstract |
A polarimetry technique for measuring optical activity that is particularly suited for high throughput screening employs a chip or substrate ( 22 ) having one or more microfluidic channels ( 26 ) formed therein. A polarized laser beam ( 14 ) is directed onto optically active samples that are disposed in the channels. The incident laser beam interacts with the optically active molecules in the sample, which slightly alter the polarization of the laser beam as it passes multiple times through the sample. Interference fringe patterns ( 28 ) are generated by the interaction of the laser beam with the sample and the channel walls. A photodetector ( 34 ) is positioned to receive the interference fringe patterns and generate an output signal that is input to a computer or other analyzer ( 38 ) for analyzing the signal and determining the rotation of plane polarized light by optically active material in the channel from polarization rotation calculations. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11143649-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9638632-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10627396-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9562845-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10261013-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011299081-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10900961-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9562853-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11293863-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9273949-B2 |
priorityDate |
2004-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |