http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8133690-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1f8af525eda6633fe8d563373041ce8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_57ccdb0f181d80e5c2199b5823285d67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58dd1b9ee029e8624927a291a28d703b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 |
| filingDate | 2009-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e638f07bd8dd39660fc238e8f424a66f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3c2f9f2078e7b9bc9e6561b52d51772 |
| publicationDate | 2012-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8133690-B2 |
| titleOfInvention | Method for inhibiting the formation of SET1 family core complexes |
| abstract | Disclosed in this specification is a method for inhibiting the formation of SET1 family core complexes. A guanidinium-containing molecule is used to competitively inhibit the binding of the N-SET region of a SET1 protein to WDR5, thus inhibiting the formation of the SET1 family core complex. The guanidinium-containing molecule may be, for example, an arginine-containing peptide. When bound to WDR5, the guanidinium moiety is bound between the F-133 and F-263 residues of the WDR5 when a crystal structure of the bound complex is obtained. |
| priorityDate | 2008-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.