http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8110193-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f47c750954e13a1ed0be96c1bf1c51c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e94b9b38f260722ef5a8dc28577f7ff |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39541 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2008-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5af458b0d2f672b91075be1755f05505 |
| publicationDate | 2012-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8110193-B2 |
| titleOfInvention | Methods for conditioning a subject for hematopoietic cell transplantation |
| abstract | Allogeneic hematopoietic cell transplantation (HCT) is an effective therapy for treatment of hematological malignancies and various autoimmune conditions. However, HCT traditionally requires conditioning by total body irradiation and/or chemotherapy, both of which are toxic and induce GVHD. Provided herein are compositions and methods for conditioning a subject for HCT by administering one or more anti-CD3 compounds and one or more histone deacetylase inhibitors. Also provided herein are methods for reducing GVHD in a subject receiving total body irradiation prior to HCT comprising administering one or more anti-CD3 compounds to the subject prior to total body irradiation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015166660-A1 |
| priorityDate | 2007-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 420.