http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8106224-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88d5399f44eb1e7e43bffcefc713ee97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e98cc62718e7f2f12731ec17fd9f3ca2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4e20d1dedbfe6c64b437eabbb5b225d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62a3119a692179555302c0a34599f4c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bde26aaf518e7fa51f478741feebd0a5 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
filingDate | 2009-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67724d691daa64bb093138135782b447 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_151e861db4242d53dfa32b1fff25b10b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92974850f12b3311f45d2bce709708b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7affbc2af95afad10fbb1ffe1542b6e5 |
publicationDate | 2012-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-8106224-B2 |
titleOfInvention | Stereospecific method for the preparation of dioxa-bicyclooctane nitrate compounds |
abstract | This invention relates to a new method for the stereospecific thiocarboxylation and nitration of organic compounds for the preparation of compounds according to formula (I): comprising the following steps: (a) reacting a compound of formula (II): with a sulfonic derivative of formula (III) wherein the R is chosen from the groups C1-3-alkyl, C1-3-alkyl substituted with 1 to 3 halogen atoms, phenyl, C1-3-alkyl-phenyl and C1-3-alkyl-phenyl wherein the alkyl is substituted with 1 to 3 halogen atoms and G is a halogen atomo or a group —O—SO2—R wherein R is as hereinabove defined to yield a compound of formula (IV) (b) treating compound (IV) with a thiocarboxylic acid of formula (V) or a salt thereof: wherein Z is as defined above, to yield compound (VI) and (c) treating compound (VI) with tetrabutylammonium nitrate to yield a compound of formula (I). |
priorityDate | 2008-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 305.