| abstract |
The present invention provides novel D-ring and side-chain analogs of 1α,25-dihydroxyvitamin D 3 , compositions comprising these compounds and methods of using these compounds as selective inhibitors of CYP24. In particular, the compounds of the invention are useful for treating diseases which benefit from a modulation of the levels of 1α,25-dihydroxyvitamin D 3 , for example, cell-proliferative disorders. |