| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_220502f4465d0df4f6e058e25e45d626
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e1ed5a22fac737f6382b1e1cf3e1dd7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5df1806cf7b0e593fd0c36b2a3f42e53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b5ab4e7cc6676862ef82426bae33765
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_804b2e4a60e5ddf9833b59f75772fc17 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-0651
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-0602
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-0661 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-0601
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-062
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B18-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-06 |
| filingDate |
2006-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d5194e01af1c1df0c2b826da5dc65b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b08fc05d2dea3b855bfb1f7c0db27581
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cf6ef1c8c1bc255c9059538f87b5db7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23f899384f980e9cc88bca83e4f1711b |
| publicationDate |
2012-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8097028-B2 |
| titleOfInvention |
Photoreactive system and methods for prophylactic treatment of atherosclerosis |
| abstract |
The present invention provides a prophylactic light activated treatment method for subjects at risk of a plaque-mediated thrombotic event, such as acute coronary syndromes. In one embodiment, the subject receives a dose of photosensitizer sufficient to result in a concentration of photosensitizer in the neovascularization associated with atherosclerotic disease to permit effective photodynamic therapy. Light of a wavelength that excites the photosensitizer, but that does not to any significant extent penetrate to an adventitial layer of the blood vessel, is applied to the region of the blood vessel. The therapeutic light dose, which may be applied in sequential stages, is sufficient to cause closure of neovasculature leakage and lead to plaque stabilization and reduced adverse clinical outcomes. The present invention further provides light transmission devices and systems useful in carrying out the methods of the present invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9541647-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015212200-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012283802-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022204131-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013301043-A1 |
| priorityDate |
2005-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |