Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9465b67919fe0e419d468cab875744d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bebbc4bbec787bb6deceb798d7300647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_821159116a8fe02a8887bef3c613ebef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee3fc660c5a6d3ea4a5c7706d479f81d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1dd98ad4ee076841fec541542f952f58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f975def7525d3da3730a107aec28b3c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c442c90823dc5b273d7ba54c630f3bfd |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-54 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-54 |
filingDate |
2010-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e02e6013bb56f9e4bfd134b45e8ba4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a78a7809bdc106d233f7ed39072b31ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb33f0ebdcc987a9c3f729f96bff7891 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_813e5339b792a31d6b6203ed904730b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_742741b77685486c4ef39abfb1771979 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a069d0dc045eb9a1d7b16d3410aba9cc |
publicationDate |
2012-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8088595-B2 |
titleOfInvention |
Method for glucose monitoring using fluorescence quenching |
abstract |
This disclosure relates to a method of measuring a glucose concentration metric or a glucose metric in a patient by contacting an implantable glucose-sensing device with a test sample, which may be in the patient, under conditions that permit a sugar-binding molecule and a functionalized polymer or nano-particle ligand present throughout the matrix of a hydrogel to interact in a glucose-dependent manner to produce an optical signal resulting from quenching of a first fluorophore linked to the ligand or sugar-binding molecule and having a fluorescent emission spectrum quenched upon binding or release of glucose. Next the first fluorophore may be excited with light of a certain wavelength. Then at least one wavelength of light in the glucose-dependent optical signal from the fluorophore may be detected with a detector to produce a detected light signal, which may be processed to produce a glucose metric, such as a glucose concentration metric. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10463287-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9834805-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9828620-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9739746-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11331018-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9829491-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9855359-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10575765-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10871487-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9750445-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10010272-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10117613-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9037205-B2 |
priorityDate |
2005-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |