http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8080676-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_001d5051bd783ef56800cfd1a863318f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_956577c94261f6fa2b8edae0c84e1b6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1d8cbf77516e7977b8d3a5861d2c886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_696ca0ae93d5cf5a686273601361781f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-66 |
| filingDate | 2007-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62b20c6a025a04d5fe102315779b50e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc9b7a1b746626558223482f4f0e9c6c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22122c110db432358572018d68194e3c |
| publicationDate | 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8080676-B2 |
| titleOfInvention | Method of producing S-(−)-6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid and product obtained by the method |
| abstract | The present invention provides an industrially available method for efficiently producing high-purity S-(−)-6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid excellent in solid-liquid separability from an S-(−)-6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid ester, and also provides products obtained by the method. Under a temperature condition of 50-80° C. in an aqueous solvent, (A) an S-(−)-6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid ester represented by the general formula (1) is hydrolyzed under a basic condition for 1-3 hours; then (B) the insoluble matters contained in the reaction solution resulting from the hydrolysis are removed; and (C) an acid is added to the resulting solution to effect crystallization; provided that R in the general formula (1) represents an alkyl or aryl group. |
| priorityDate | 2006-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.