Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4fa917ffec6660de001b9c190e13812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56557f11a262e490544e32c6fa0f7805 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed97891110d90bb2a4e948e403f7f621 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_923cfb0612d8b5c968aa090cb692c235 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1658 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
filingDate |
2009-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2428b41a4720f2ccc902462170bad552 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06ca0c943c659e8085de64b3e94f1d0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_922afd50f6ca569f929f3ba2be0705c7 |
publicationDate |
2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8080515-B2 |
titleOfInvention |
Method for prevention of platelet aggregation employing and RGD-enriched gelatine-like protein |
abstract |
The invention concerns a cell support comprising an RGD-enriched gelatine that has a more even distribution of RGD sequences than occurring in a natural gelatine and with a minimum level of RGD sequences. More precise the percentage of RGD sequences related to the total number of amino acids is at least 0.4 and if the RGD-enriched gelatine comprises 350 amino acids or more, each stretch of 350 amino acids contains at least one RGD motif. Preferably the RGD-enriched gelatines are prepared by recombinant technology, and have a sequence that is derived from a human gelatine or collagen amino acid sequence. The invention also relates to RGD-enriched gelatines that are used for attachment to integrins. In particular The RGD-enriched gelatines of the invention are suitable for coating a cell culture support for growing anchor-dependant cell types. Further, the RGD-enriched gelatines of the invention may find use in medical applications, in particular as a coating on implant or transplant material or as a component of drug delivery systems. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9115183-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011207669-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8557774-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013260456-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8961929-B2 |
priorityDate |
2003-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |