| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_64b04e2a53766b3f0dde1200e6e88d86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58ebac9263232d73a07ba94f82987e9c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdd4f7191c7b37e35e082ab795c810f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e04a9c30b01a6909696dc92e883f241c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1d51d308434831954b5e42b949ec6cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70df3056b4703146f2926f20b90008fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_886ff27cb1526d935eb09e5b5c515c36 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-734
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-732 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
2008-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_549dbe90edba6f123e67e6f8e6a316b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4ab4bfdf1267bf0739467a54e96e27f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1c7b84271db4440493c3a1b9020e053
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25fe652ddabb0c754ee2b982edbf9556
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ec1a41d1645ca10ee7375c99d7abec7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbddc36b34977403d590134ae050894f |
| publicationDate |
2011-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8076458-B2 |
| titleOfInvention |
Anti-claudin-4 antibody |
| abstract |
An object of the present invention is to provide a monoclonal antibody which is useful as a diagnostic agent or a therapeutic agent for a disease relating to a polypeptide encoded by Claudin-4 (hereinafter referred to as “CLDN4”) gene or a polypeptide encoded by a Claudin-3 (hereinafter referred to as “CLDN3”) gene, or a method for using the same. Accordingly, the present invention provides a monoclonal antibody or an antibody fragment thereof, which specifically recognizes three-dimensional structure of an extracellular region of CLDN4 and binds to the extracellular region; a monoclonal antibody or an antibody fragment thereof, which specifically recognizes three-dimensional structure of both of extracellular regions of CLDN3 and CLDN4 and binds to the extracellular regions; a hybridoma which produces the antibody; a DNA which encodes the antibody; a vector which comprises the DNA; a transformant obtained by transforming the vector; a process for producing an antibody or an antibody fragment thereof using the hybridoma or the transformant; and a diagnostic agent or a therapeutic agent for a disease relating to a polypeptide encoded by CLDN4 gene and/or CLDN3 gene using the antibody or the antibody fragment. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11773173-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10544227-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10053511-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11260125-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10253091-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11723976-B2 |
| priorityDate |
2007-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |