http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8052961-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a49a0b30981e68d61bdeb9913842a504 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C247-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-21 |
| filingDate | 2007-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59af704f8909c1843faafc0326cd3e89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df438399d2854a0592e9fff462eca54e |
| publicationDate | 2011-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8052961-B2 |
| titleOfInvention | Highly fluorinated β-amino acids and methods of making and using same |
| abstract | Disclosed are compounds having the structure: n nwherein R 1a and R 1b are independently H, alkyl, F, or fluoroalkyl; wherein R 2a , R 2b , R 2a′ , and R 2b′ are independently H, alkyl, F, fluoroalkyl, aryl, or alkenyl; wherein R 3 is OH, alkoxyl, NH 2 , alkylamino, or dialkylamino; wherein R 4a and R 4b are independently H, alkyl, acyl, or alkyloxycarbonyl; wherein R 11 , R 12 , R 13 , R 21 , R 22 , and R 23 are independently H, alkyl, F, or fluoroalkyl; and wherein C0, C1, C2 and C2′ are independently chiral or achiral. Also disclosed are processes for making a fluorinated β-amino acid comprising the steps of: providing a diol; treating the diol with a thionyl halide with oxidative workup; reacting the product with an azide salt to yield an azido group; oxidizing the product to yield a carboxyl group; and reducing the azido group to yield an amino group. |
| priorityDate | 2006-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 240.