Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-56 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-62 |
filingDate |
2008-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5337b01a0ada4dbf55294d22bf93f2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3c4a16c7b35cb54f562281965e65dcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fe03c58d0902c6bfad06be28a59e6c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f9c2a9b467e17bab3d70d8aab30c204 |
publicationDate |
2011-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8044186-B2 |
titleOfInvention |
Heterologous production of capreomycin and generation of new capreomycin derivatives through metabolic engineering |
abstract |
Provided are nucleic acid molecules comprising at least a functional fragment of the capreomycin biosynthetic gene cluster, polypeptides encoded by the cluster and recombinant host cells transformed with any of the nucleic acid molecules disclosed herein. Various methods using any of the vectors or expression cassettes that encode one or more of the gene products of the cluster are provided for heterologous production of capreomycin and capreomycin derivatives. |
priorityDate |
2007-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |