Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb141b396e502bfce986c491d722e401 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2835 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4703 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
filingDate |
2006-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d5b528a88d8fe77cea579b5015ef711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_472a0818b1cec05364a59d7203ba23f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d6da5121dad2619d6b7b2c3df9fab49 |
publicationDate |
2011-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8039209-B2 |
titleOfInvention |
Yeast screens for treatment of human disease |
abstract |
Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided using a yeast system. The methods of the invention provide a rapid and cost-effective method to screen for compounds that prevent protein misfolding and/or protein fibril formation and/or protein aggregation which includes numerous neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, Huntington's disease as well as non-neuronal diseases such as type 2 diabetes. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9518284-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9738898-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11401325-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106803-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10428335-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011053857-A1 |
priorityDate |
2001-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |