| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e400c7cafe4d27546b9127d5fdd3312b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C47-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-516
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-001 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C47-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-00 |
| filingDate |
2009-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0601c43a722fe1eb6f06dc677c488cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3dabfac9f4f2a67b322997fd678ead8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e772c8a893375c7bb4f837490d887125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf6bafed9252caa7e14e5c372ca55e4e |
| publicationDate |
2011-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8030526-B2 |
| titleOfInvention |
Simple, rapid method for the preparation of isotopically labeled formaldehyde |
| abstract |
Isotopically labeled formaldehyde (*C § H 2 O) is prepared from labeled methyl iodide (*C § H 3 I) by reaction with an oxygen nucleophile having a pendant leaving group. The mild and efficient reaction conditions result in good yields of *C § H 2 O with little or no *C isotopic dilution. The simple, efficient production of 11 CH 2 O is described. The use of the 11 CH 2 O for the formation of positron emission tomography tracer compounds is described. The reaction can be incorporated into automated equipment available to radiochemistry laboratories. The isotopically labeled formaldehyde can be used in a variety of reactions to provide radiotracer compounds for imaging studies as well as for scintillation counting and autoradiography. |
| priorityDate |
2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |