Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5dd388a5130b0bdede0fdfc6c2af6ed |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4606 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2006-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0facf81d82682324f16b6cced73c60e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d063777527592e23cb1144aa0c9402b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7c89c9ed71aeb3579468ef3bb0d99c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0568bcbb136ff3af555a7bf4ce4fdbcf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19791d462f83cdc61697364891cbfb45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be21cd2448ee088d51b83a3a4c316c43 |
publicationDate |
2011-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8030004-B2 |
titleOfInvention |
Cell free screening assay and methods of use |
abstract |
Methods are disclosed for identifying agents for the treatment of cancer and/or Fanconi anemia using Xenopus egg cell free extracts from which the endogenous DNA has been removed. The assays and method described herein are easily adaptable to high throughput techniques for example to screen large numbers of agents as possible agents for the treatment of cancer and/or Fanconi anemia. Kits for carrying out the disclosed assays and methods also are disclosed. Agents identified by these methods are also disclosed as are methods for treating a subject with cancer and/or Fanconi anemia with these agents. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9980729-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9974538-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9962158-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010240645-A1 |
priorityDate |
2005-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |