| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c999fee6428152a996011d506925c2d7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0016
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-08 |
| filingDate |
2008-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_668b9953a3198a5860d4c21f91b0f435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b9aa03f3046100807c0e7af29553252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e0f5f94132f903e52de3d0f48150a23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24c1e93be6690b1d7071fc0967b71828 |
| publicationDate |
2011-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8017363-B2 |
| titleOfInvention |
Method for production of L-lysine using methanol-utilizing bacterium |
| abstract |
A method for production of L-lysine is provided which includes the steps of cultivating a methanol-utilizing bacterium in a culture medium to produce and accumulate L-lysine in the culture medium and collecting the L-lysine from the culture medium, wherein the methanol-utilizing bacterium contains DNA encoding dihydrodipicolinate synthetase which is desensitized to feedback inhibition by L-lysine and DNA encoding a LysE protein that can enhance the excretion of L-lysine out of the methanol-utilizing bacterium, and the bacterium is modified so as to increase the intracellular activities of diaminopimelic acid dehydrogenase, diaminopimelic acid decarboxylase, dihydrodipicolinic acid reductase and aspartate-semialdehyde dehydrogenase. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9506094-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10400257-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11098329-B2 |
| priorityDate |
2006-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |