http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8013155-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e70c0aeade92d7571d955d3b90ea06e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-46 |
| filingDate | 2006-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d576d371bf51d4d9baf353bc8df92e34 |
| publicationDate | 2011-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8013155-B2 |
| titleOfInvention | Method for preparing substituted pyrimidines |
| abstract | Disclosed a method for preparing a compound of Formula 1, n nwherein R 1 is cyclopropyl, 4-chlorophenyl or 4-bromophenyl; and R 2 is C 1 -C 14 alkyl; comprising contacting a compound of Formula 2n n nwith a persulfate oxidant in the presence of a strong sulfur- or phosphorus-containing mineral acid and an oxidation resistant solvent. Also disclosed are methods for preparing the compound of Formula 2 from a compound of Formula 5n n nas well as compounds of Formula 6 and salts thereof,n n n n n n n n n n n n n wherein R is NH 2 , Cl or OH; X is H or Cl; R 1 is cyclopropyl, 4-chlorophenyl or 4-bromophenyl; and R 2 is C 1 -C 14 alkyl; provided that when R is NH 2 or Cl, then X is Cl; which are useful a process intermediates. |
| priorityDate | 2005-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 183.