| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1d1be6200bb60f340e388868edadc71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_895d0945c751742e1089822fbc7d25bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7b56f8e9a6b41d26bfb8f3da696c09d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75340acb75e7522ea270faf62d315b4a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7323408bb1dd9c6e51c5dabd5c47bf4f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-706 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| filingDate |
2008-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed6a6f8f24cdc503e1400043ee65e1e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56f8ba3b387f8a2fe7b50e597be3a8d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c5e25f1d30e2a24377d3f2fdebf0783
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4b1e468ba33b28a4fc64f861e9f1302
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a59b566ed0004846fc24178650d2bd36 |
| publicationDate |
2011-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8008000-B2 |
| titleOfInvention |
Viral variants detection and application |
| abstract |
The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B virus (HBV) variants exhibiting complete or partial resistance to nucleoside or nucleotide analogs and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity to these antibodies. The present invention further contemplates assays for detecting such viral variants, which assays are useful in monitoring anti-viral therapeutic regimens and in developing new or modified vaccines directed against viral agents and in particular HBV variants. The present invention also contemplates the use of the viral variants to screen for and/or develop or design agents capable of inhibiting infection, replication and/or release of the virus. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021096829-A1 |
| priorityDate |
2003-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |