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filingDate 2009-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2011-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2011-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8003327-B2
titleOfInvention Methods of screening for risk of proliferative disease and methods for the treatment of proliferative disease
abstract A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore.
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