Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4322cb4de342be2dbedcbe0c278f6f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
filingDate |
2009-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2151acdc742570fcac26f15b3ed5dc74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89b7ab6c4eb1a734d0b86cb674427c40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a2d21fd93b23e77db86877cd0160fa0 |
publicationDate |
2011-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8003327-B2 |
titleOfInvention |
Methods of screening for risk of proliferative disease and methods for the treatment of proliferative disease |
abstract |
A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010152123-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8242086-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012052504-A1 |
priorityDate |
1998-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |