| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_717c792fca7cc9c290c9db33e8fe078b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001182
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001186
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00117
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001151
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001181
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-02 |
| filingDate |
2006-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7f683110f0dd6bdf966808615005ced
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60baacd11d71d8cae8e99e6e8e70ab7c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4811101ed29c9653ae34dce7195d2d1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99277d2679d9ba11ede3e1f69587c69b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d84e4ed309272afe00fb2ebb614eb8f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_021af62a93fa7a5891020e77403821ca |
| publicationDate |
2011-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8003093-B2 |
| titleOfInvention |
B cell-based vaccine loaded with the ligand of natural killer T cell and antigen |
| abstract |
The present invention relates to a B cell-based vaccine loaded with the ligand of natural killer T cell and antigen for the prevention and treatment of disease, more precisely, an immunotherapeutic and prophylactic vaccine mediated by B cells loaded with α-galactosylceramide, a kind of glycolipid which can stimulate natural killer T cells. A vaccine composition of the present invention can be effectively used as an antitumor immunotherapeutic agent. B cells therein, which are easily obtainable compared with dendritic cells, not only induce a similar level of cytotoxic T lymphocyte response to that of the conventional dendritic cell-based vaccine but also have a prophylactic and therapeutic effect on solid tumor and metastatic tumor. |
| priorityDate |
2006-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |