| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4463c01a3ae0fffbe8002848c98ac9b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-32 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G63-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G63-91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K3-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K3-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F283-00 |
| filingDate |
2008-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a04a2ff126e7a741943d2b90d1496848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e8da6c06fc5675333537505965877f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01e82ee02566c5d0d8df8d907712da13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a82b531537606da4b595fc23015fe29f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5407c667c4ad38a8f6b5db634fd46ee2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8cd4c4ba8eb8a12b43687dccc4277c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe40f5a841698e0548313a052878f14d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3934e8c124fee08272951fd4918ef2af |
| publicationDate |
2011-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7989532-B2 |
| titleOfInvention |
RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) / β tricalcium phosphate composite material and preparation method thereof |
| abstract |
An RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/β-tricalcium phosphate composite material is composed of β-tricalcium phosphate particles and RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) with mass ratio of 1:10-1:100, in which the β-tricalcium phosphate particles are uniformly dispersed in the RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) matrix. The preparation method includes that poly (glycolic acid-L-lysine-L-lactic acid) is polymerized with GRGDY short peptide (glycin-arginine-glycin-aspartic acid-tyrosine sequence) to obtain RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid), and then RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) is compounded with β-tricalcium phosphate particles. The composite material exhibits favorable biocompatibility, cellular affinity, biodegradability and mechanical behavior, and can avoid aseptic necrosis of tissues, which may be used as nerve guide or porous bone scaffold for repairing nerve tissue and bone tissue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10457660-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8685432-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9284294-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9011832-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10207030-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9447068-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9452143-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9655863-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10584306-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9889235-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009324683-A1 |
| priorityDate |
2006-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |