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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6848
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34
filingDate 2005-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2011-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cb2a035ba3569b5bd1670591d8c2f22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_198477d9e61daeb5c6920a75c7e90769
publicationDate 2011-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7989169-B2
titleOfInvention Selective amplification of methylated nucleic acids
abstract The invention is related to a method for amplifying a methylated target nucleic acid in a sample while avoiding amplification of a non-methylated target nucleic acid by inactivating it. This is accomplished by a restriction enzyme digest after bisulfite treatment of the target nucleic acid. The invention is further related to the use of a restriction enzyme to avoid amplification of a non-methylated target nucleic acid while amplifying a methylated target nucleic acid in a sample and kits for performing the methods according to the invention.
priorityDate 2004-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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