http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7977320-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
filingDate | 2005-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e074dfc0eec0b2f5e7f81d2a406dac58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bb22f2f897a6e8816bba55ed3d3ecc5 |
publicationDate | 2011-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7977320-B2 |
titleOfInvention | Method of increasing efficacy of tumor cell killing using combinations of anti-neoplastic agents |
abstract | The present invention provides compositions and methods for increasing the amount of active Syk protein kinase and or SHP-1 protein phosphatase in a cell. The compositions and methods are useful for increasing the efficacy of anti-neoplastic agents, such as those that target the CD33 protein, and which are used to treat leukemia. The invention thus provides for treatment of cancers, including leukemias. The invention also provides screening assays for anti-neoplastic agents in vitro. Methods of screening patients for responsiveness to anti-CD33 treatments are also provided. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010160412-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8372582-B2 |
priorityDate | 2004-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.