http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7972615-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b52ce3ac639d5adbf74ac5b47526901 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 |
filingDate | 2009-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92d72935bb40d80f9bdf6e1557db80b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28df8d07552ca95c7dd3db011cdd5dac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75f2737511a519083265a747ef8df7fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72ded054f35cd565b156c5d6f10f852e |
publicationDate | 2011-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7972615-B2 |
titleOfInvention | Peptide compositions for coating metal medical devices with vancomycin |
abstract | The presently disclosed subject matter provides compositions comprising a first substrate-binding domain (a peptide or a polymer) having binding affinity for a tissue or a medical device, a second substrate-binding domain having binding affinity for a target molecule, and the target molecule. In some embodiments, the first and second substrate-binding domains are covalently linked. The first and second substrate-binding domains are covalently coupled to at least one hydrophobic interaction tag, negatively charged interaction tag, or positively charged interaction tag. When the substrate-binding domains are combined and coated onto the tissue or medical device, the hydrophobic interaction tags interact with each other and the charged interaction tags interact with the oppositely charged interaction tags or the oppositely charged substrate binding polymers, to form a macromolecular network of non-covalently coupled substrate-binding domains to load the target molecule onto the tissue or medical device. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10191036-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8697655-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013045917-A1 |
priorityDate | 2008-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 656.