http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7964209-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_029116ee41eeec8a03f88a8cddbaa758 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-60 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B05D3-02 |
| filingDate | 2004-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b68693e0ef1abb61bec470c552311c61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_484e09040cdbafb8cd7c1782a5054058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_688c96cff11158af098272693cddd084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e574b57779512a19f68c7ed84cbe2d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87771bd681ac5becc69de36ac7246a34 |
| publicationDate | 2011-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7964209-B2 |
| titleOfInvention | Orienting polymer domains for controlled drug delivery |
| abstract | The present invention provides a method for the formation of a medical device that comprises a therapeutic agent and a release region, which regulates the rate at which the therapeutic agent is released from the medical device. The method comprises providing a precursor region that comprises a polymer composition comprising two or more microphase separated polymer domains that are immiscible with one another, and forming said release region by a process that comprises applying an orienting field comprising an electric field, a magnetic field, a mechanical shear field, or a solvent gradient field, or a combination of two or more fields to said precursor region, wherein said field or combination of fields changes the spatial orientation of the microphase separated polymer domains within the release region. The electric, magnetic, mechanical shear or solvent gradient field is of sufficient strength to change the spatial orientation of the microphase separated domains. Moreover, the spatial orientation of the immiscible microphase separated polymer domains affects the rate of release of the therapeutic agent from the medical device. Hence, the present invention is further directed to methods of modulating the rate of release of a therapeutic agent from a medical device. Other aspects of the invention are directed to medical devices formed from the above techniques. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8545867-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011150972-A1 |
| priorityDate | 2004-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 744.