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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6408
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-48
filingDate 2009-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2011-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa311818d4aef53c27b390ed7d06bf6e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fa962e6e3f31344be5396db8995f38e
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publicationDate 2011-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7960162-B2
titleOfInvention Protein having prolyl oligopeptidase activity, nucleic acid encoding same and method for producing and using same
abstract Proteins isolated from Coprinus clastophyllus having prolyl oligopeptidase activity, nucleic acids encoding the protein and methods for producing and using the protein, wherein SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:9 and SEQ ID NO:10 must be contained therein to at least 60% similarity. The proteins and nucleic acids have improved heat stability and perform more favorably in vivo having optimum activity conditions around 40 degrees centigrade and around pH 7, and can therefore be used in medicaments for the treatment of celiac disease caused by proline abundant gluten or other applications.
priorityDate 2008-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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