| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 |
| filingDate |
2007-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1c9723c7eeb2647b6161c989591ce33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3186759c2e91dea8445cb9c17a2c24ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_596652c7e542e7af819f306d0eafd3fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b111f9c767cce3d42aae9be426cdf44f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f3f435574f24da58cc60b7df1267c5f |
| publicationDate |
2011-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7935791-B2 |
| titleOfInvention |
Antagonist anti-Notch3 antibodies and their use in the prevention and treatment of Notch3-related diseases |
| abstract |
The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10407500-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022235127-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9523695-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8513388-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3611189-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9914774-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018009889-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10627409-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017290844-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016007775-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11453718-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8187839-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10538587-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8956811-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011206675-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11142573-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9933434-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9518124-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11536727-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014159239-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10900973-B2 |
| priorityDate |
2006-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |