Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f210e3b9a1e1a33ae59a32a78cd5b05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate |
2007-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68daaaec1bf7dc951e6d147b8adff6b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30a28eed5d112abb2ccc448278b6299d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_344cfe6b338035191f50310045cf6cf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f205e3160e9c62932e65dc5301262ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a93bd9c50d67d93df6bcd1604ec89034 |
publicationDate |
2011-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7935354-B2 |
titleOfInvention |
Generation of new BCG vaccine strains protecting against the establishment of latent Mycobacterium tuberculosis infection and reactivation from the latent or persistent state |
abstract |
A vaccine for treating or preventing the establishment of latent tuberculosis infections is provided. The vaccine comprises a recombinant mycobacterium that overexpresses the transcription factor DosR, at a level sufficient to induce production of the dosR regulon genes or proteins. A host to whom the vaccine is administered mounts an immune response to the dosR regulon proteins and is thus protected from the establishment, persistence or reactivation of latent tuberculosis. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I458978-B |
priorityDate |
2007-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |