http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7935350-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d552ad67a0c5088d1dd230735e4ae6a1 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55516 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001106 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 |
| filingDate | 2007-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20a423fe1ee86f43f59161fc9c7b405e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e377b02b8eee4455455c91fb48e9737a |
| publicationDate | 2011-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7935350-B2 |
| titleOfInvention | Ii-key/Her-2/neu hybrid cancer vaccine |
| abstract | Provided are methods and compositions for treating cancer in humans, the cancer being characterized by expression of Her-2/neu. The methods involve vaccinating a patient with an Ii-Key/MHC class II hybrid construct and thereby stimulating an immune response to the native Her-2/neu protein. The construct may be in the form of an Ii-Key hybrid peptide or a nucleic acid encoding an Ii-Key hybrid peptide. Methods are described wherein the cancer being treated is breast cancer. Also claimed is a pharmaceutical composition comprising an Ii-Key/MHC class II hybrid construct with and without an adjuvant. The adjuvant can include GM-CSF. The Ii-Key hybrid construct includes the LRMK (SEQ ID NO: 2) residues of Ii-Key protein and an MHC Class II epitope of a protein or portion thereof which is used in the vaccine or a DNA encoding the same hybrid peptide. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104327158-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104327158-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9732150-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014271464-A1 |
| priorityDate | 2006-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.