| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f62b36b442d05acbbbd8a50348777098 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2510-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5079
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate |
2008-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da1d49ef592d03eae7f3e7cb961351b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0264a4790e0af8f4bff886ed278aa67 |
| publicationDate |
2011-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7927816-B2 |
| titleOfInvention |
Methods for identifying modulators of apoptosis |
| abstract |
The invention provides a method of identifying an effective compound that modulates the binding of Humanin to Bax or Bid. The invention also provides a method of identifying an effective compound that modulates an activity of Bax or Bid. In addition, the invention provides a method of identifying a Humanin-like compound that binds to Bax or Bid or modulates an activity of Bax or Bid, or inhibits the apoptotic activity of Bax or Bid. The invention further provides an isolated polypeptide containing a mitochondrial-derived form of Humanin (SEQ ID NO:3) or a functional fragment thereof where the fragment contains the methionine at position 16 of SEQ ID NO:3. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014030725-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9359635-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10077433-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9879306-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9248201-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9757478-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9290794-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9290745-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9045730-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9339561-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013053323-A1 |
| priorityDate |
2001-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |