Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_449898f4ff389ba06802c9f48c6a132c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C321-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-44 |
filingDate |
2008-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be6659730f39f4bf6eff3dc8f2b8ea8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2b6dc69c5cc22f29dc30649355e1226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca987b5eb825cc36acaa891072e17c93 |
publicationDate |
2011-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7915449-B2 |
titleOfInvention |
Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation |
abstract |
The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:n a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent; and optionally b) isolating the obtained sulphoxide of formula (I). nn n n n n n n n n n n n wherein n, Y, R 1 , R 1a , R 2 and R 2a are as defined. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8759583-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8318979-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012123161-A1 |
priorityDate |
2003-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |