Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e70c0aeade92d7571d955d3b90ea06e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
filingDate |
2009-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b831da14cb328fb75b16f48a495a17b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f18807fcf8caba35dd9d99cd391996c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcf4f3ca6fd2067e180dc38d32126295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a8c08552946037b2b224b662ca0acde http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3bdf9f05815b4c7c334663166141e52 |
publicationDate |
2011-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7915011-B2 |
titleOfInvention |
Host cell modifications that improve peptide production and downstream processing |
abstract |
Disrupting the expression of endogenous Escherichia host cell genes gcvA and spr provides mutant host cells having increased heterologous peptide production. The addition of a genetic modification to the coding region of gene yejM further enhances peptide production and facilitates easier downstream processing. Recombinant Escherichia host cells are provided as well as methods of using such host cells for heterologous peptide production. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8288137-B2 |
priorityDate |
2009-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |