http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7914766-B1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00
filingDate 2004-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2011-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbd20ea539fa10edfac6483670dab64b
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publicationDate 2011-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7914766-B1
titleOfInvention Inorganic resins for clinical use of 213Bi generators
abstract Applicant's invention is a radionuclide generator resin material for radiochemical separation of daughter radionuclides, particularly 213 Bi, from a solution of parental radionuclides, the resin material capable of providing clinical quantities of 213 Bi of at least 20-mCi, wherein the resin material comprises a silica-based structure having at least one bifunctional ligand covalently attached to the surface of the silica-based structure. The bifunctional ligand comprises a chemical group having desirable surface functionality to enable the covalent attachment of the bifunctional ligand thereon the surface of the structure and the bifunctional ligand further comprises a second chemical group capable of binding and holding the parental radionuclides on the resin material while allowing the daughter radionuclides to elute off the resin material. The bifunctional ligand has a carbon chain with a limited number of carbons to maintain radiation stability of the resin material.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015066356-A1
priorityDate 2004-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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