Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77d9bf55e6700374867763cc2c6acaff http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07b71571160c289fbf5fc680dfea513f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7151 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-563 |
filingDate |
2008-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79192a03ec6a2d55f58aa178ccb82c43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1502c8c5ddaab27680af1c646759aa0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9b8fe21772b13ed8c9d259a35b48629 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_689d2594fe6919c78d0d7a3868af53d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e147c6cefbff1c700fb285fe83515ce |
publicationDate |
2011-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7910321-B2 |
titleOfInvention |
Methods of determining the level of human tumor necrosis factor receptor-like 2 |
abstract |
The present invention relates to novel members of the Tumor Necrosis Factor family of receptors. The invention provides isolated nucleic acid molecules encoding a human TR2 receptor and two splice variants thereof. TR2 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TR2 receptor activity. Also provided are diagnostic methods for detecting disease states related to the aberrant expression of TR2 receptors. Further provided are therapeutic methods for treating disease states related to aberrant proliferation and differentiation of cells which express the TR2 receptors. |
priorityDate |
1995-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |