| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4b760959bd9eac6001d9ad59dd24b10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca3ccdc009f33d70da2f2894479f59e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad97948cdd048d5564afe99e914a2734 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-24011 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-555 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate |
2009-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13c8f180caabbf2af11b6498f5c0d5ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4af4a881af49dd49c146206f41cc2e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a52725993e3d698642e55c63aea8ae7 |
| publicationDate |
2011-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7888475-B2 |
| titleOfInvention |
Interferon alpha and interferon kappa fusion protein |
| abstract |
Herein is described a system to combat poxvirus infection wherein antagonists are developed that bind the soluble cytokine receptor but have no significant biological activity in the host, effectively blocking the virus-mediated suppressor of interferon function, thereby permitting the host's own cytokines to stimulate an antiviral response. Alternatively, interferon molecules can be developed that retain biological activity on their native receptors but fail to bind the viral cytokine binding protein, thereby circumventing this virus immune modulation mechanism. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11788213-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017123548-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10919950-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10876227-B2 |
| priorityDate |
2008-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |