http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7888024-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d5d546aa6cbfb52c137af7cafc36bf4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
| filingDate | 2008-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_537206f7a9d15c0087ff45f3da62157b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51322355dc513b8f3565ab325319efde http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0fc1b88093d6ed2fc3800a0ab569b3e |
| publicationDate | 2011-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7888024-B2 |
| titleOfInvention | Method of detecting genetic polymorphism |
| abstract | The present invention provides a novel polymorphism detecting method suitable for the detection and identification of copy number variation. n Provided is a method of determining the genotype of a subject in a genomic region comprising an SNP site, comprising a step for performing typing of the SNP site by the invader assay with a DNA-containing sample comprising the genomic region from the subject as the template, wherein fluorescence is measured on a real time basis. The copy number ratio of both alleles is determined using the fluorescence intensity ratio of each allele at a time before saturation of fluorescence intensity. Preferably, the present method further comprises a step for amplifying the genomic region comprising an SNP site prior to the invader step. In this step of amplification, a plurality of regions comprising a plurality of SNP sites can be simultaneously amplified. Furthermore, the present method enables the determination of the copy number of each allele when combined with quantitative PCR. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11251595-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11094398-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018144449-A1 |
| priorityDate | 2007-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.