Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_634d7355c2673489b2f4f800541770bb |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-726 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-723 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B15-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06G7-58 |
filingDate |
2005-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0cbd215e842b4e3ce5e16fd8a6cddb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d75092ca3c57ff7e328c8e1c7f1b254 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5088cc9a46748c9e25e3de1fe78550f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7332689e38fba08cd0aaf466577e75f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e37d9538aa85707675e07c78f9c5c5b |
publicationDate |
2011-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7869958-B2 |
titleOfInvention |
Structure-based modulators of B1 G-protein coupled receptors |
abstract |
The present invention relates to a method for identifying modulators of B1 G-protein coupled receptors. The present invention also relates to a method for identifying an antagonist or agonist of the corticotropin-releasing factor receptor 2 (CRFR2). The present invention also relates to a method for improving antagonists or agonists of CRFR2. The present invention also relates to the three-dimensional structure of CRFR2 as representative of the B1 GPCR subfamily and its use as a basis for rational drug design of antagonist or agonists of B1 GPCRs. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013063046-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011054776-A1 |
priorityDate |
2004-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |