http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7868180-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_207c148d0cfc11d05383db5abcce58d3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-00 |
| filingDate | 2006-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b254d988122f999f6aa46ebc03357ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc4841803dec795d1fcfc0e3ee8dc9f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5d172817451c0e73b64166f81a38d6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f0349ba7152ffa11ac7760c41046f00 |
| publicationDate | 2011-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7868180-B2 |
| titleOfInvention | Process for the preparation of sartan derivatives and intermediates useful in such process |
| abstract | The invention provides a process for the preparation of a sartan derivative of formula (I) (formula as filed in paper form) (I) wherein the substituents have the meaning indicated in the description, or a pharmaceutically acceptable salt thereof, comprising reacting 2-cyanophenylboronic acid or a derivative thereof with a p-halobenzyl-1H-imidazole derivative of formula (VI), (formula as filed in paper form) (VI) wherein (part of formula as filed in paper form), X, Y, R 1 and R 2 are as defined above, and Z is I, Br or Cl, in the presence of a transition metal catalyst and an inorganic or organic base. The invention also provides new intermediates of formula (V), (formula as filed in paper form) (V) wherein M is an alkali metal or an NR 4 R 5 R 6 R 7 group; and of formula (II) (formula as filed in paper form) (II). |
| priorityDate | 2005-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 364.