| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_644c03c3333a4447130f6dd66cfccfc4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-33303
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G79-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G79-08 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G73-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G79-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G79-02 |
| filingDate |
2006-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06183f53ea393b7dc8b3654f119f7803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ff2672412949f33c6da8b24ad13a2c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfe79bf1401580d01251ab90a91a5edb |
| publicationDate |
2011-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7868131-B2 |
| titleOfInvention |
Methods of preparing polymers having terminal amine groups |
| abstract |
The present invention is directed to methods of preparing linear polymers such as polyalkylene oxides containing a terminal amine in high purity. One preferred method includes reacting a polyalkylene oxide such as polyethylene glycol containing a terminal azide with a phosphine-based reducing agent such as triphenylphosphine or an alkali metal borohydride reducing agent such as sodium borohydride in a solvent to reflux. The resultant polymer-amines are of sufficient purity so that expensive and time consuming purification steps required for pharmaceutical grade polymers are avoided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11584923-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9969998-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8846875-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013041140-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016061286-A2 |
| priorityDate |
2005-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |