| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12936a430b83d792f6361d58ccd1f934 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2264
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-26 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
2004-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_702604ad63b3b7dee566d47fbde11a09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67dfbc2eb0fa084cc00d0c4be834403c |
| publicationDate |
2011-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7863240-B2 |
| titleOfInvention |
Methods and uses of leptin in hepatocellular carcinoma |
| abstract |
The present invention relates to methods for the modulation of immune responses. More particularly, the invention relates to methods and uses of leptin for immuno-modulation of the balance between the Th1/Th2 responses and for the treatment of immune-related disorders. Specifically, the methods of the invention comprise shifting the Th1/Th2 cell balance towards the proinflammatory state. This modulation of the cell balance may be performed by increasing the activity and/or the expression of leptin in said subject, for instance by raising the amount of leptin. The amount of leptin in a subject may be increased by activating immunoregulatory cells, administering an immunomodulatory amount of leptin or a homologue, derivative, or functional fragment of leptin. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009291894-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11608381-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10253102-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10550192-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8716220-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11535675-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010113358-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10618968-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8642543-B2 |
| priorityDate |
2004-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |