| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae220374ed7bff2d640abcd35cde17f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d8e2f4547a15621fa0c4fbdc64719f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_998e177cc94ff7736082885eceb64669
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0bd13b432c0f7fa85df4097cc7ea906c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94745c9d311f4783f4de7e2dc99a7b31 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0012 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-724
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| filingDate |
2005-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d87b5cb01806c6266a7cf8f70c29c0d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4fc9af0ed85529a96a7ab47bd9008e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35138d3c3abaf11c34230330602e84d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c30e127db2682990d8503b2ad82945aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b65b886d26340ed4d0252cd62e3005d9 |
| publicationDate |
2010-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7834174-B2 |
| titleOfInvention |
Per-6-guanidino-, alkylamino-cyclodextrins, methods of their synthesis and their use for the compaction of DNA and intercellular delivery |
| abstract |
The invention relates to new compounds of type hexakis(6-deoxy-6-NH(CH 2 ) n —R 1 )α-cyclodextrin and heptakis(6-deoxy-6-NH(CH 2 ) n —R 1 )-(β-cyclodextrin, and octakis(6-deoxy-6-NH(CH 2 ) n —R 1 )-γ-cyclodextrin, where n=2-6 when R 1 =NH 2 and n=0 when R 1 =C(═NH)NH 2 and n=2-6 when R 1 =NH—C(═NH)NH 2 and their use in the compaction of DNA and in cell permeation. The invention also relates to methods of synthesis of the above compounds. |
| priorityDate |
2004-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |