http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7820851-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_487f95154be3da3497db1e7dcb4fdeb0 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C53-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C53-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-63 |
filingDate | 2007-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2010-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f5e22227bae8d98247a1b2fb71fd012 |
publicationDate | 2010-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7820851-B2 |
titleOfInvention | Isotopically labeled polyfluorinated compound useful as an imaging tracer |
abstract | A polyfluorinated compound is provided inclusive of at least one 18 F atom having a formula:n nCF 3 (CF 2 ) n R 1 (I)n nwhere R 1 is —C(O)OR 2 , —C(O)N(R 3 ) 2 , C—N(R 3 ) 2 , —C(NR 3 )R 2 , C-QR 3 , -QR 3 , —N + (R 3 ) 3 , X, C 1 -C 30 alkyl, C 1 -C 30 haloalkyl, C 1 -C 30 alkoxyl, or C 1 -C 30 perhaloalkyl; R 2 is M Z+ , H, C 1 -C 12 alkyl, C 1 -C 12 alkyl, C 1 -C 12 perhalo alkyl, C 6 -C 30 aryl, C 6 -C 30 perhaloaryl, and a substituted form thereof where one or more protons or halogens is replaced with a plasma solubility enhancing moiety of —N + (R 3 ) 3 , —SO 3 H, —SO 2 N(R 3 ) 2 , or -QR 3 ; R 3 is independently in each occurrence M Z+ , —SO 3 H, —SO 2 N(R 3 ) 2 , or -QR 3 ; Q is O or S; M Z+ is a cation that forms a net neutral compound with an anionic (CF 3 (CF 2 ) n C(O)O − ) Z and is an alkali metal cation, an alkali earth cation, a transition metal cation, ammonium, and aluminum cations; Z is an integer value of between 1 and 3 inclusive; X is a fluorine, chlorine, bromine or iodine atom; halo denotes a replacement of at least one and not all protons with X; perhalo denotes a replacement of all protons with X; and n is an integer value of between 1 and 30 inclusive. |
priorityDate | 2006-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 170.