| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1d1b5eb8d4613e5b917c656d29fd775 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
| filingDate |
2004-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c4b437038139c417efcd8427b20923f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5a0a79fca2a44fcdbc3489bc4389cc9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0fc27e9109db7edc2b14b475a84a4dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5937b673a3750f3c1a7ba333eed72b22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a548c0fe63e661f4354d9762f797fb44 |
| publicationDate |
2010-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7820808-B2 |
| titleOfInvention |
Polymerase inhibitor and method of using same |
| abstract |
The present invention provides nucleic acid based polymerase inhibitors and methods for reducing non-specific polymerase extension and amplification in nucleic acid amplification reactions. The polymerase inhibitors provide a double stranded nucleic acid portion that is recognized by a polymerase enzyme as a template for extension but is incapable of being extended by the polymerase enzyme. The polymerase binds to the polymerase inhibitor which sequesters the enzyme until the temperature achieves a level that denatures the double stranded portion of the inhibitor after which the polymerase is released and can then catalyze nucleic acid extension. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11225686-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011160289-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10604796-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011111462-A1 |
| priorityDate |
2003-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |