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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
filingDate 2007-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2010-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2047b1b0fecdf6f6355c2634db848047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ae5903cf10bed07c6035a36335cb572
publicationDate 2010-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7803556-B2
titleOfInvention Plant PR-5 proteins as mammalian therapeutic agents
abstract The Proteins of the PR-5 family having a lectin-like β barrel domain control apoptosis in yeast through receptor binding. Receptors that specifically bind to PR-5 proteins having a lectin-like β barrel domain have been found to be homologous to mammalian adiponectin receptors, and such PR-5 proteins can act as functional homologues of adiponectin and control adiponectin response in mammals. PR-5 proteins having a lectin-like β barrel domain, for example osmotin, can be used in the treatment of conditions in mammals which are the result of activation or inhibition of adiponectin receptor-mediated metaboloic pathways. PR-5 proteins having a lectin-like β barrel domain, nucleic acids encoding such proteins, and receptors that specifically bind such proteins, can also be used in screening and rational design of new therapeutic agents for use in mammals.
priorityDate 2004-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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