| abstract |
The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one compound having the general formula (A): n nwherein U is N or C; X is selected from C 1 -C 10 alkylene, C 2-10 alkenylene or C 2-10 alkynylene, where each may include one or more intrachain heteroatoms selected from O, S, or NR 11 , provided any such heteroatom is not adjacent to the N in the ring; R 3 is selected from aryl, aryloxy, arylthio, cycloalkyl, cycloalkenyl, cycloalkynyl, aryl-N(R 10 )—, or heterocycle, where each said substituent is optionally substituted with at least one R 17 , provided that for cycloalkenyl the double bond is not adjacent to a nitrogen; and the other substituents are described in the specification.n n The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula, their pharmaceutically acceptable formulations and their use as a medicine or to treat or prevent viral infections. |