Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed28726de9f916f355f8adc331e736b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2feed77ad2920b465a9409f31480591 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39735fa0a2330b2dd4fe6ed188468ac5 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55511 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-739 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-739 |
filingDate |
2004-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2010-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5015dff1e873259f83cb54446ad3f80f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bacfb770a907983613f4d9103d0efec7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e04a0297f63b48105f5d2cc80db5013c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b9cafbbb12e73bd8c99ecef1f9da519 |
publicationDate |
2010-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7771726-B2 |
titleOfInvention |
Use of synthetic glycolipids as universal adjuvants for vaccines against cancer and infectious diseases |
abstract |
The present invention relates to methods and compositions for augmenting an immunogenicity of an antigen in a mammal, comprising administering said antigen together with an adjuvant composition that includes a synthetic glycolipid compound of Formula I, as described herein. According to the present invention, the use of a compound of Formula I as an adjuvant is attributed at least in part to the enhancement and/or extension of antigen-specific Th1-type responses, in particular, CD8+ T cell responses. The methods and compositions of the present invention can be useful for prophylaxis and treatment of various infectious and neoplastic diseases. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10603369-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10842868-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9950062-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10098949-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014308313-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10052373-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009304743-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2077855-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9375471-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9315530-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9931399-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2851092-A1 |
priorityDate |
2003-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |