| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9aaad810d986791598c15c3682bdc60 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C403-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-203 |
| filingDate |
2008-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adda1b82890f52c32ea3fe6ad473056e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_213d0840cbcf7588d6808257699b69f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a04a044feab2e7a2ace5ad07059d4b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1370310ff69a402e7c3d71893fbacfa0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c18adcd1078c6f4c60eeae8f82d2a2d2 |
| publicationDate |
2010-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7763748-B2 |
| titleOfInvention |
Process for preparation of highly pure isotretinoin |
| abstract |
The present invention relates to a process for preparation of isotretinoin and more specifically, to a purification process for obtaining highly pure isotretinoin that is useful as a keratolytic agent, particularly useful for the treatment of acne. The process involves treating isotretinoin containing metal contamination and/or other impurities with a base in a suitable solvent to form a solution of isotretinoin, followed by adsorption, precipiation, and filtration or centrifugation. |
| priorityDate |
2007-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |