| abstract |
A prostaglandin derivative represented by Formula (I): n nwherein X is a halogen atom in the α- or β-substitution, Y is an ethylene group, a vinylene group or an ethynylene group, R 1 is a C 3-10 cycloalkyl group, a C 3-10 cycloalkyl group substituted with a C 1-4 straight or branched chain alkyl group or a C 4-13 cycloalkylalkyl group, R 2 is a hydrogen atom or a CO 2 R 3 group (R 3 is a hydrogen atom, a C 1-4 straight or branched chain alkyl group or a C 2-4 straight or branched chain alkenyl group), n is an integer of 1 to 4 and p is 0, 1 or 2,n na pharmaceutically acceptable salt thereof or a hydrate thereof. |